Guinea is to be declared free of Ebola by the World Health Organization (WHO), two years after the epidemic began there.
Guineans are expected to celebrate the landmark with concerts and fireworks.
The disease killed more than 2,500 people in the country and a further 9,000 in Sierra Leone and Liberia.
Sierra Leone was declared free of Ebola in November, but new cases have emerged in Liberia, which had been declared Ebola-free in September.
A country is considered free of human-to-human transmission once two 21-day incubation periods have passed since the last known case tested negative for a second time.