Manjula Vithlani, aged 68, was rushing upstairs to check on her son Ashish, who had developed breathing problems.
But as she tried to reach the landing, she slipped and fell on her husband Natvarlal, following behind.
He suffered head injuries after being crushed underneath his wife, who weighed 20 stone.
Manjula also died of cerebral haemorrhage in the freak accident in Ramdham, India on Monday.
The couple died after they were admitted to a private hospital in the area.