New Prime Minister Theresa May has made Boris Johnson, the former London mayor who led the Brexit campaign, foreign secretary in her new government.
He replaces Philip Hammond, who becomes chancellor. Ex-Energy Secretary Amber Rudd is home secretary and Eurosceptic David Davis is the Brexit secretary.
The UK's second female prime minister promised to give people who were "just managing" and "working around the clock" more control over their lives.
Downing Street said she took a number of "congratulatory phone calls" from other European leaders on Wednesday evening, where she told them "some time" would be needed to prepare for EU exit talks.
In her appointments announced so far, Michael Fallon continues as defence secretary, and Liam Fox, who resigned as defence secretary in 2011, has a new role as secretary of state for international trade.