India overcame stubborn resistance from South Africa to win the fourth and final Test in Delhi by 337 runs and seal a 3-0 series victory.
Resuming on 72-2 on the final day in pursuit of a notional 481, the tourists were bowled out shortly after tea for 143, made in 143.1 overs.
Hashim Amla fell early for 25 off 244 balls and AB de Villiers 43 off 297.
The tourists lost their last five wickets for seven runs after tea as Ravichandran Ashwin claimed 5-61.
It was the off-spinner's fourth five-wicket haul of a series in which he took 31 wickets at an average of only 11.12.