Former Ireland and Lions captain Paul O'Connell has been forced to retire from rugby with immediate effect.
Lock O'Connell quit international rugby after injuring a hamstring during a 2015 World Cup group game with France.
He signed a two-year contract with Toulon but never played for the French side after failing to regain fitness.
"It is with deep regret that I have decided to retire from professional rugby following medical advice," said O'Connell, 36.
"Since sustaining the injury at the World Cup I have been fully focused on returning to fitness and starting an exciting new chapter for both myself and my family in Toulon. Unfortunately this will no longer be possible."
O'Connell, who had a long domestic career with his home province of Munster during which he won two Heineken Cups, earned 108 caps for Ireland and seven caps for the British and Irish Lions.
He captained his country 28 times and also led the Lions in three Tests.