England completed their first series victory in India for 27 years as Jonathan Trott and Ian Bell both hit centuries on the final day in Nagpur.
Trott scored 143 and Bell 116 not out as the tourists - who lost in Ahmedabad before winning in Mumbai and Kolkata - earned the draw they needed to secure an historic achievement.
India took just one wicket all day as debutant Joe Root added an unbeaten 20.
England finished 356 runs ahead on 352-4 when stumps were drawn early.
Their final-day dominance was fitting because, since being beaten by nine wickets in the first Test, England have outplayed their hosts in every department.